Viagra Super Active

Viagra Super Active is the most advanced form of Viagra. It contains the active ingredient sildenafil and is used to treat erectile dysfunction in men.

Indications for use

The drug is used to treat erectile dysfunction, characterized by an inability to achieve or maintain an erection of the penis sufficient for satisfactory intercourse. The drug is effective only with sexual stimulation.

How does it work?

Sildenafil restores decreased erectile function by increasing blood flow to the penis. The mechanism of action is based on the release of nitric oxide in the corpora cavernosa at the time of sexual arousal. Free nitric oxide activates the enzyme guanylate cyclase, stimulating an increase in cGMP levels, which causes relaxation of the smooth muscle fibers of the corpora cavernosa and increased blood flow.

How to take Viagra Super Active?

The drug is taken orally.

The recommended dose for most adult patients is 50 mg approximately 1 hour before sexual activity. Taking into account the efficacy and tolerability, the dose can be increased to 100 mg or reduced to 25 mg. The maximum recommended dose is 100 mg. The maximum recommended frequency of use is 1 time / day.

Contraindications

  • Peyronie’s disease;
  • Penile anuglation;
  • Cavernous fibrosis of the penis;
  • Increased tendency to bleeding;
  • Functional failure of the liver;
  • Liver cirrhosis;
  • Various diseases that cause priapism;
  • Sickle cell anemia;
  • Various heart diseases;
  • Individual intolerance to sildenafil or its components;
  • Arrhythmia;
  • Ulcerative lesion of the stomach in the acute phase;
  • Ulcerative lesion of the duodenum in the acute phase;
  • Leukemia;
  • Various anatomical pathologies of the penis;
  • Multiple myeloma;
  • Decreased level of general blood pressure in severe form;
  • Increased level of general arterial pressure in severe form;
  • Use with drugs from the group of nitric oxide donors;
  • Use with drugs from the nitrate group;
  • Not used in women;
  • Not used in men under 18 years.

Side effects

  • General disorders: chest pain, general weakness;
  • Allergic reactions: hypersensitivity reactions (including skin rash), Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell’s syndrome);
  • Central and peripheral nervous system: drowsiness, hypesthesia, stroke, fainting, transient ischemic attack, convulsions, incl. recurrent;
  • Cardiovascular system: tachycardia, increase or decrease in blood pressure, myocardial infarction, atrial fibrillation, ventricular arrhythmia, unstable angina pectoris, sudden death;
  • Respiratory organs: epistaxis;
  • Digestive system: vomiting, nausea, dryness of the oral mucosa;
  • Eyes: eye pain, redness of the eyes/sclera injection, conjunctival damage, impaired lacrimation, anterior ischemic optic neuropathy, retinal vascular occlusion, visual field defects;
  • Hearing organ: vertigo, tinnitus, deafness;
  • Musculoskeletal system: myalgia;
  • Reproductive system: prolonged erection and/or priapism, hematospermia and bleeding from the penis.

Overdose

When using Viagra Super Active in doses higher than recommended, the adverse events were similar to those noted above but usually more common. Treatment is symptomatic. Hemodialysis does not accelerate the excretion of the drug since sildenafil strongly binds to blood plasma proteins and is not excreted by the kidneys.

Interaction with other drugs

Avoid using Viagra Super Active with any of the following drugs:

  • CYP3A4 inhibitors (erythromycin, cimetidine);
  • indinavir, saquinavir, ritonavir;
  • stronger inhibitors of the CYP3A4 isoenzyme such as ketoconazole or itraconazole;
  • nitrates;
  • simvastatin.

Pregnancy and breastfeeding

The drug is not intended for use in women.

Special instructions

Before taking sildenafil for the treatment of erectile dysfunction, a patient needs to undergo a cardiovascular examination.

The drug is used with caution in patients having anatomical deformity of the penis (for example, angulation, cavernous fibrosis or Peyronie’s disease) and patients with diseases that predispose to priapism (such as sickle cell anemia, multiple myeloma, or leukemia).

The medicine is not used in patients who are not recommended to have sexual activity.

The drug is used with caution in patients having a tendency to bleeding, gastric ulcer and duodenal ulcer in the acute phase, hereditary retinitis pigmentosa.

The drug has no effect on the ability to drive or use machinery.