Kamagra is a medication used to treat erectile dysfunction. It contains the active ingredient sildenafil citrate, which is used in Viagra,
When is Kamagra used?
The drug is used in men with erectile dysfunction (inability to achieve or maintain an erection of the penis, ensuring successful sexual intercourse).
How does it work?
Sildenafil restores decreased erectile function by increasing blood flow to the penis. The mechanism of action is based on the release of nitric oxide in the corpora cavernosa at the time of sexual arousal. Free nitric oxide activates the enzyme guanylate cyclase, stimulating an increase in cGMP levels, which causes relaxation of the smooth muscle fibers of the corpora cavernosa and an increase in blood flow.
How to take Kamagra?
The drug is taken orally approximately 1 hour before sexual activity. Swallow the tablet whole and drink a little water. When taken on an empty stomach, the drug starts working faster.
Use strictly under medical supervision.
For most patients, the recommended dose is 50 mg.
Taking into account the effectiveness and tolerability, the maximum single dose can be increased to 100 mg or decreased to 25 mg.
The drug should be taken no more than once a day.
Any changes in the dosage of the drug must be agreed with a doctor.
Kamagra is not used in the following conditions:
- hypersensitivity to any component of the drug;
- use with drugs that are donors of nitric oxide;
- organic nitrates or nitrites in any form;
- heart failure;
- unstable angina pectoris, suffered in the last 6 months of heart attack;
- myocardial, stroke, or life-threatening arrhythmias;
- arterial hypertension;
- or arterial hypotension;
- established congenital degenerative diseases of the retina (retinitis pigmentosa, a congenital defect of retinal phosphodiesterases);
- children and adolescents under the age of 18 years;
- not intended for use on women.
Common side effects:
- visual impairment (violation of color perception, increased sensitivity to light or blurred vision);
- face flushing;
- nasal congestion, flu-like syndrome;
Rare side effects:
- mydriasis, conjunctivitis, photophobia, pain in the eyes, bleeding in the eyes;
- tinnitus, ear pain;
- shortness of breath, cough, laryngitis, pharyngitis, sinusitis, bronchitis, asthma;
- palpitations, tachycardia, syncope, low blood pressure;
- postural arterial hypotension, peripheral edema, ischemia;
- myocardium, cerebral thrombosis, delay of the next;
- heartbeat, heart failure, abnormalities on the electrocardiogram, atrioventricular block, angina pectoris;
- dry mouth, thirst, vomiting, stomatitis, gingivitis, glossitis, dysphagia;
- esophagitis, gastritis, gastroenteritis, colitis, rectal bleeding;
- chest pain, general weakness;
- back pain;
- arthralgia, myalgia, tendon rupture, tendovaginitis, myasthenia gravis, synovitis;
- arthritis, arthrosis;
- ataxia, neuralgia, neuropathy, paresthesia, trembling, depression;
- drowsiness, insomnia, sleep disturbance, decreased reflexes, hypesthesia;
- urticaria, herpes simplex, skin rash, itching, increased sweating, skin ulcers, contact dermatitis;
- cystitis, nocturia, frequent urination, urinary incontinence;
- swelling of the mammary glands, impaired ejaculation, edema of the genitals and anorgasmia;
- anemia, leukopenia;
- hyperglycemia, hypoglycemia, hyperuricemia, hypernatremia;
- cerebrovascular disorders, syncope;
- myocardial infarction, atrial fibrillation;
- arterial hypertension;
- nose bleed.
High doses of the drug may cause an increase in side effects. Overdose treatment is symptomatic and supportive.
Interaction with other drugs
Do not take Kamagra with nitro-containing drugs, nicorandil, alpha-blockers and poppers as this can cause a sharp uncontrolled drop in blood pressure.
We strongly recommend that you read the full instructions for use and get a doctor’s advice! Improper use can be harmful to health!
Do not take Kamagra if you are taking ketoconazole, itraconazole, fluconazole, erythromycin, clarithromycin, and cimetidine, as this may cause an overdose. The interval between taking sildenafil and these funds should be at least 72 hours.
Do not combine this medication with other drugs based on cGMP inhibitors – specific type 5 phosphodiesterase (Viagra, Cialis, Levitra, etc.).
Interaction with alcohol and foods
The use of Kamagra with food disrupts the absorption of the active substance into the blood, which delays the effect of the drug. Do combine the medicine with alcohol as this can cause a sharp and uncontrolled decrease in blood pressure and life-threatening complications.
It is not recommended to take these pills with grapefruit juice because it can increase the content of the active substance in the blood plasma, which may lead to overdose symptoms.
Pregnancy and breastfeeding
The drug is not intended for use in women.
A medical history and physical examination should be done to diagnose erectile dysfunction, identify potential underlying causes, and treat the disease appropriately. There is some cardiovascular risk associated with sexual activity; therefore, a doctor needs to assess the patients’ cardiovascular system before prescribing any drugs for the treatment of erectile dysfunction.
Kamagra should be used with caution in patients with anatomical deformity of the penis (angular curvature, cavernous fibrosis, or fibroplastic induration of the penis (Peyronie’s disease), or in patients with concomitant diseases that can cause priapism (such as sickle cell anemia, multiple myeloma) or leukemia).
The safety and effectiveness of the drug in combination with other drugs for the treatment of erectile dysfunction have not been studied. Therefore, it is not recommended to use the drug in combination with such drugs.
Kamagra has no effect on bleeding time, either when the drug is taken alone or together with aspirin. Human platelets have shown that the drug enhances the antiplatelet effect of sodium nitrocyanide (nitric oxide donor). There are no data on the safety of taking the drug in patients with bleeding disorders or active peptic ulcers. Therefore, the drug should be used with caution in such patients.
Some patients with hereditary retinal pigmentary degeneration have a genetic disorder of retinal phosphodiesterase. There are no data on the safety of taking sildenafil pills in patients with retinal pigmentary degeneration. Therefore, the drug should be used with caution in such patients.
In the course of numerous studies, it has been proven that the drug does not violate the reaction rate when driving and working with moving mechanisms. However, we recommend that you find out your individual medicine tolerance before driving or working with moving machinery.